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Article

A model system for increased meiotic nondisjunction in older oocytes.

Current biology : CB - 18 Mar 2003

Jeffreys Charlotte A, Burrage Peter S, Bickel Sharon E

Abstract excerpt

For at least 5% of all clinically recognized human pregnancies, meiotic segregation errors give rise to zygotes with the wrong number of chromosomes. Although most aneuploid fetuses perish in utero, trisomy in liveborns is the leading cause of mental retardation. A large percentage of human triso...

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Identifiers

PMID: 12646133
DOI: 10.1016/s0960-9822(03)00134-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12646133-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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