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Article

Amyloid beta and impairment in multiple memory systems in older transgenic APP TgCRND8 mice.

Genes, brain, and behavior - 1 Oct 2009

Hanna A, Horne P, Yager D, Eckman C, Eckman E, Janus C

Abstract excerpt

The relationship between amyloid beta and cognitive dysfunction in mouse models of Alzheimer's disease has been evaluated predominantly with the spatial reference memory version of the water maze task. However, as Alzheimer's disease encompasses decline in multiple memory systems, it is important to also utilize non-spatial tasks to fully characterize the role of amyloid on behaviour in animal models. We used the...

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Source

Identifiers

PMID: 19531156
DOI: 10.1111/j.1601-183X.2009.00510.x

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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