Article
Changes in allele-specific association of histone modifications at the imprinting control regions during mouse preimplantation development.
Genesis (New York, N.Y. : 2000) - 1 Sept 2009
Kim Jin-Moon, Ogura Atsuo
Abstract excerpt
Allele-specific association of histone modification is observed at the regulatory region of imprinted genes and has been suggested to work as an epigenetic marker for monoallelic gene expression, along with the allelic CpG methylation of DNA. Although the parent-origin-specific epigenetic status in imprinted genes is thought to be established during preimplantation development, little is known about the allelic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
