Article
Establishment and characterization of three novel cell lines - P-STS, L-STS, H-STS - derived from a human metastatic midgut carcinoid.
Anticancer research - 1 Jun 2009
Pfragner Roswitha, Behmel Annemarie, Höger Harald, Beham Alfred, Ingolic Elisabeth, Stelzer Ingeborg, Svejda Bernhard, Moser Victor Aguiriano, Obenauf Anna Christina, Siegl Veronika, Haas Oskar, Niederle Bruno
Abstract excerpt
Carcinoids are rare tumors derived from enterochromaffin (EC) cells of the embryonic neural crest. They have malignant potential and their incidence is steadily increasing. The only curative treatment option is surgery. We have focused on cultivation of human neuroendocrine tumors (NET) as relevant models for the study of potential therapy. Only a few cell lines from human carcinoids have been established so far,...
Topics
- Adult
- Animals
- Carcinoid Tumor
- Chromosomes, Human, Pair 18
- Comparative Genomic Hybridization
- Cryopreservation
- Enterochromaffin Cells
- Female
- Humans
- Ileal Neoplasms
- Immunoenzyme Techniques
- Lung Neoplasms