Article
A unique neuroendocrine cell model derived from the human foetal neural crest.
Journal of endocrinological investigation - 1 Sept 2020
Rapizzi E, Benvenuti S, Deledda C, Martinelli S, Sarchielli E, Fibbi B, Luciani P, Mazzanti B, Pantaleo M, Marroncini G, Vannelli G B, Maggi M, Mannelli M, Luconi M, Peri A
Abstract excerpt
PURPOSE: Nowadays, no human neuroendocrine cell models derived from the neural crest are available. In this study, we present non-transformed long-term primary Neural Crest Cells (NCCs) isolated from the trunk region of the neural crest at VIII-XII gestational weeks of human foetuses obtained from voluntary legal abortion. METHODS AND RESULTS: In NCC, quantitative real-time RT PCR demonstrated the expression of...
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