Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

doi:10.1111/j.1600-0897.2009.00709.x

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Article

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Jul 2009

Vargas Rafael Gustavo, Bompeixe Eni Picchioni, França Patrícia Pinhode, Marques de Moraes Marcio, da Graça Bicalho Maria

Abstract excerpt

PROBLEM: Natural killer (NK) cells are regulated through NK cell receptors such as killer cell immunoglobulin-like receptors (KIRs). KIRs are suspected of being involved in the causes of recurrent miscarriage (RM) as a higher proportion of activated NK cells were observed in women with RM when compared with that in controls. The aim of this study was to investigate if KIR genes coding for receptors known to have...

Topics

Abortion, Habitual
Adult
Case-Control Studies
Female
Gene Frequency
Genetic Predisposition to Disease
HLA Antigens
Humans
Killer Cells, Natural
Male
Pregnancy
Receptors, KIR

Source

Open in PubMed

Identifiers

PMID: 19527230
DOI: 10.1111/j.1600-0897.2009.00709.x

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