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Article

Increased activating killer immunoglobulin-like receptor genes and decreased specific HLA-C alleles in couples with recurrent spontaneous abortion.

Biochemical and biophysical research communications - 31 Aug 2007

Wang Shan, Zhao Yue-Ran, Jiao Yu-Lian, Wang Lai-Cheng, Li Jian-Feng, Cui Bin, Xu Cheng-Yan, Shi Yu-Hua, Chen Zi-Jiang

Abstract excerpt

Accumulating evidence indicates natural killer (NK) cells play crucial roles in successful pregnancy. To investigate whether the killer cell immunoglobulin-like receptor (KIR) gene polymorphism and the corresponding specific HLA ligands in parent couples possessing a susceptibility to unexplained recurrent spontaneous abortion (RSA), we searched 73 pairs of childless couples with three or more abortions...

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Share to Abortion, Spontaneous
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

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Share to Polymorphism, Genetic

Share to Receptors, Immunologic

Share to Receptors, KIR

Share to Receptors, KIR2DL1

Source

Identifiers

PMID: 17617375
DOI: 10.1016/j.bbrc.2007.06.125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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