Article
Polymorphic variation of genes in the fibrinolytic system and the risk of ovarian cancer.
PloS one - 15 Jun 2009
Bentov Yaakov, Brown Theodore J, Akbari Mohammad R, Royer Robert, Risch Harvey, Rosen Barry, McLaughlin John, Sun Ping, Zhang Shiyu, Narod Steven A, Casper Robert F
Abstract excerpt
INTRODUCTION: The etiology of ovarian cancer is largely unknown. One hypothesis is that the inefficient removal of the blood clots and fibrin products which are deposited in the vicinity of the ovary by retrograde menstruation might be associated with an increased risk of ovarian cancer. Several single nucleotide polymorphisms within genes which comprise the fibrinolytic system have been shown to have functional...
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