Article
Genetic polymorphism in the fibrinolytic system and endometriosis.
Obstetrics and gynecology - 1 Jul 2006
Bedaiwy Mohamed A, Falcone Tommaso, Mascha Edward J, Casper Robert F
Abstract excerpt
OBJECTIVE: Although most women experience retrograde menses during their reproductive life, endometriosis develops only in a small percentage. We hypothesized that persistence of a fibrin matrix in peritoneal pockets, as a result of hypofibrinolysis, could allow menstrually deposited endometrial fragments to initiate endometriosis. Fibrinolysis is modulated by several factors, and polymorphisms in the plasminogen...
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