Article
Variability in C-type lectin receptors regulates neuropathic pain-like behavior after peripheral nerve injury.
Molecular pain - 10 Dec 2014
Dominguez Cecilia A, Carlström Karl E, Zhang Xing-Mei, Al Nimer Faiez, Lindblom Rickard P F, Ortlieb Guerreiro-Cacais Andre, Piehl Fredrik
Abstract excerpt
INTRODUCTION: Neuropathic pain is believed to be influenced in part by inflammatory processes. In this study we examined the effect of variability in the C-type lectin gene cluster (Aplec) on the development of neuropathic pain-like behavior after ligation of the L5 spinal nerve in the inbred DA and the congenic Aplec strains, which carries seven C-type lectin genes originating from the PVG strain. RESULTS: While...
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