Article
KTN (RCK) domains regulate K+ channels and transporters by controlling the dimer-hinge conformation.
Structure (London, England : 1993) - 10 Jun 2009
Roosild Tarmo P, Castronovo Samantha, Miller Samantha, Li Chan, Rasmussen Tim, Bartlett Wendy, Gunasekera Banuri, Choe Senyon, Booth Ian R
Abstract excerpt
KTN (RCK) domains are nucleotide-binding folds that form the cytoplasmic regulatory complexes of various K+ channels and transporters. The mechanisms these proteins use to control their transmembrane pore-forming counterparts remains unclear despite numerous electrophysiological and structural st...
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