Article
Serotype and genotype replacement among macrolide-resistant invasive Pneumococci in adults: mechanisms of resistance and association with different transposons.
Journal of clinical microbiology - 1 Apr 2010
Calatayud Laura, Ardanuy Carmen, Tubau Fe, Rolo Dora, Grau Immaculada, Pallarés Román, Martín Rogelio, Liñares Josefina
Abstract excerpt
The aim of this study was to analyze trends in adult invasive pneumococcal disease (IPD) due to macrolide-resistant strains and to study the evolution of serotypes, genotypes, and macrolide-resistant determinants of strains collected in a prospective study between 1999 and 2007 in Barcelona, Spain. IPD due to macrolide-resistant strains of serotypes included in the 7-valent conjugate vaccine (PCV7) decreased from...
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