Article
Levofloxacin-resistant invasive Streptococcus pneumoniae in the United States: evidence for clonal spread and the impact of conjugate pneumococcal vaccine.
Antimicrobial agents and chemotherapy - 1 Sept 2004
Pletz Mathias W R, McGee Lesley, Jorgensen James, Beall Bernard, Facklam Richard R, Whitney Cynthia G, Klugman Keith P
Abstract excerpt
The emergence of fluoroquinolone resistance in sterile-site isolates of Streptococcus pneumoniae is documented in this study characterizing all invasive levofloxacin-resistant (MIC, > or = 8 mg/liter) S. pneumoniae isolates (n = 50) obtained from the Centers for Disease Control and Prevention Active Bacterial Core Surveillance from 1998 to 2002. Resistance among all isolates increased from 0.1% in 1998 to 0.6% in...
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