Article
Levofloxacin-resistant invasive Streptococcus pneumoniae in the United States: evidence for clonal spread and the impact of conjugate pneumococcal vaccine.
Antimicrobial agents and chemotherapy - 1 Sept 2004
Pletz Mathias W R, McGee Lesley, Jorgensen James, Beall Bernard, Facklam Richard R, Whitney Cynthia G, Klugman Keith P
Abstract excerpt
The emergence of fluoroquinolone resistance in sterile-site isolates of Streptococcus pneumoniae is documented in this study characterizing all invasive levofloxacin-resistant (MIC, > or = 8 mg/liter) S. pneumoniae isolates (n = 50) obtained from the Centers for Disease Control and Prevention Act...
Topics
- Anti-Bacterial Agents
- Drug Resistance, Bacterial
- Electrophoresis, Gel, Pulsed-Field
- Genes, Bacterial
- Humans
- Levofloxacin
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Multigene Family
- Mutation
- Ofloxacin
- Pneumococcal Infections
- Pneumococcal Vaccines