The neurofibromatoses: when less is more.

doi:10.1093/hmg/10.7.747

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

The neurofibromatoses: when less is more.

Human molecular genetics - 1 Apr 2001

Gutmann D H

Abstract excerpt

The study of cancer predisposition syndromes presents unique opportunities to gain insights into the genetic events associated with tumor pathogenesis. Individuals with two inherited cancer syndromes, neurofibromatosis 1 (NF1) and neurofibromatosis 2 (NF2), develop both benign and malignant tumors. The corresponding genes mutated in these two disorders encode tumor suppressor proteins, termed neurofibromin (NF1)...

Topics

Animals
Cell Communication
Disease Progression
Genetic Predisposition to Disease
Humans
Immunohistochemistry
Membrane Proteins
Mice
Models, Biological
Mutation
Nerve Tissue Proteins
Neurofibromatosis 1
Neurofibromatosis 2
Neurofibromin 1
Neurofibromin 2
Proto-Oncogene Proteins p21(ras)
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 11257108
DOI: 10.1093/hmg/10.7.747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics