Article
High-throughput genotyping of KIR2DL2/L3, KIR3DL1/S1, and their HLA class I ligands using real-time PCR.
Tissue antigens - 1 Jul 2009
Koehler R N, Walsh A M, Moqueet N, Currier J R, Eller M A, Eller L A, Wabwire-Mangen F, Michael N L, Robb M L, McCutchan F E, Kijak G H
Abstract excerpt
Killer immunoglobulin-like receptors (KIRs) expressed on natural killer cells are critical components of innate immunity. Interactions between KIRs and their human leukocyte antigen (HLA) ligands have been shown to influence autoimmune and infectious disease course in defined populations. However, the low throughput and high cost of current methods impede confirmation of the universality of these findings. To...
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