Article
High-throughput killer cell immunoglobulin-like receptor genotyping by MALDI-TOF mass spectrometry with discovery of novel alleles.
Immunogenetics - 1 Jul 2007
Houtchens Kathleen A, Nichols Robert J, Ladner Martha B, Boal Hannah E, Sollars Cristina, Geraghty Daniel E, Davis Lee M, Parham Peter, Trachtenberg Elizabeth A
Abstract excerpt
The killer cell immunoglobulin-like receptors (KIR) interact with major histocompatibility complex (MHC) class I ligands to regulate the functions of natural killer cells and T cells. Like human leukocyte antigens class I, human KIR are highly variable and correlated with infection, autoimmunity,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
