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Article

High-throughput killer cell immunoglobulin-like receptor genotyping by MALDI-TOF mass spectrometry with discovery of novel alleles.

Immunogenetics - 1 Jul 2007

Houtchens Kathleen A, Nichols Robert J, Ladner Martha B, Boal Hannah E, Sollars Cristina, Geraghty Daniel E, Davis Lee M, Parham Peter, Trachtenberg Elizabeth A

Abstract excerpt

The killer cell immunoglobulin-like receptors (KIR) interact with major histocompatibility complex (MHC) class I ligands to regulate the functions of natural killer cells and T cells. Like human leukocyte antigens class I, human KIR are highly variable and correlated with infection, autoimmunity, pregnancy syndromes, and transplantation outcome. Limiting the scope of KIR analysis is the low resolution,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Killer Cells, Natural

Share to Receptors, Immunologic

Share to Receptors, KIR

Share to Receptors, KIR2DL1

Share to Receptors, KIR3DL1

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

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Identifiers

PMID: 17464504
DOI: 10.1007/s00251-007-0222-x
PMCID: PMC2881672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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