Article
Suppression of lymphocyte proliferation and regulation of dendritic cell phenotype by soluble mediators from rat lacrimal epithelial cells.
Scandinavian journal of immunology - 1 Jul 2009
de Saint Jean M, Nakamura T, Wang Y, Trousdale M D, Schechter J E, Mircheff A K
Abstract excerpt
Lacrimal epithelial cells appear to constitutively secrete autoantigens to their underling stroma. The present experiments address the hypothesis that they also secrete soluble factors that regulate immune responses. Epithelial cells, spleen cells and lymphocytes were obtained from rabbits or rats and cultured in various configurations. Monocytes from rat bone marrow were matured to dendritic cells (DC) ex vivo....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.