Article
Improved cholesterol phenotype analysis by a model relating lipoprotein life cycle processes to particle size.
Journal of lipid research - 1 Dec 2009
van Schalkwijk Daniël B, de Graaf Albert A, van Ommen Ben, van Bochove Kees, Rensen Patrick C N, Havekes Louis M, van de Pas Niek C A, Hoefsloot Huub C J, van der Greef Jan, Freidig Andreas P
Abstract excerpt
Increased plasma cholesterol is a known risk factor for cardiovascular disease. Lipoprotein particles transport both cholesterol and triglycerides through the blood. It is thought that the size distribution of these particles codetermines cardiovascular disease risk. New types of measurements can determine the concentration of many lipoprotein size-classes but exactly how each small class relates to disease risk...
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