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Article

VLDL (Very-Low-Density Lipoprotein)-Apo E (Apolipoprotein E) May Influence Lp(a) (Lipoprotein [a]) Synthesis or Assembly.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2020

Croyal Mikaël, Blanchard Valentin, Ouguerram Khadija, Chétiveaux Maud, Cabioch Léa, Moyon Thomas, Billon-Crossouard Stéphanie, Aguesse Audrey, Bernardeau Karine, Le May Cédric, Flet Laurent, Lambert Gilles, Hadjadj Samy, Cariou Bertrand, Krempf Michel, Nobécourt-Dupuy Estelle

Abstract excerpt

OBJECTIVE: To clarify the association between PCSK9 (proprotein convertase subtilisin/kexin type 9) and Lp(a) (lipoprotein [a]), we studied Lp(a) kinetics in patients with loss-of-function and gain-of-function PCSK9 mutations and in patients in whom extended-release niacin reduced Lp(a) and PCSK9 concentrations. Approach and Results: Six healthy controls, 9 heterozygous patients with familial hypercholesterolemia...

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Identifiers

PMID: 32078365
DOI: 10.1161/ATVBAHA.119.313877

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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