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Article

Peripheral inflammation sensitizes P2X receptor-mediated responses in rat dorsal root ganglion neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jan 2002

Xu Guang-Yin, Huang Li-Yen Mae

Abstract excerpt

ATP-gated P2X receptors in nociceptive sensory neurons participate in transmission of pain signals from the periphery to the spinal cord. To determine the role of P2X receptors under injurious conditions, we examined ATP-evoked responses in dorsal root ganglion (DRG) neurons isolated from rats with peripheral inflammation, induced by injections of complete Freund's adjuvant (CFA) into the hindpaw. Application of...

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Identifiers

PMID: 11756492
PMCID: PMC6757597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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