Article
Large-scale mouse mutagenesis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Cartwright Elizabeth J
Abstract excerpt
Determining gene function by using transgenesis in the mouse has been immensely popular amongst researchers since the introduction of the techniques in the 1980s. However, we are still a long way from knowing the function of the majority of the genes in the genome. It is becoming increasingly accepted that there needs to be a coherent programme of systematic mutation of every protein-coding gene in the mouse...
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