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Article

Large-scale mutational analysis for the annotation of the mouse genome.

Current opinion in chemical biology - 1 Feb 2002

Beckers Johannes, Hrabé de Angelis Martin

Abstract excerpt

After sequencing the human and mouse genomes, the annotation of these sequences with biological functions is an important challenge in genomic research. A major tool to analyse gene function on the organismal level is the analysis of mutant phenotypes. Because of its genetic and physiological similarity to man, the mouse has become the model organism of choice for the study of genetic diseases. In addition, there...

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PMID: 11827818
DOI: 10.1016/s1367-5931(01)00277-0

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Source receipt: pubmed, retrieved 7 Sept 2026.

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