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Article

The math of making mutant mice.

Genes, brain, and behavior - 1 Aug 2003

Williams R W, Flaherty L, Threadgill D W

Abstract excerpt

More than ten large-scale mutagenesis projects are now generating hundreds of novel mouse mutants. Projects employ a wide variety of strategies and screens: targeting as much as the whole genome, part of a chromosome or just single genes. In this commentary, we consider the pros and cons of different tactics. We highlight issues of cost, efficiency and defend the impact of this mutagenesis program in an era of...

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Identifiers

PMID: 12953785
DOI: 10.1034/j.1601-183x.2003.00017.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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