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Article

Genetic variation of FTO and TCF7L2 in premature adrenarche.

Metabolism: clinical and experimental - 1 Sept 2009

Lappalainen Saila, Voutilainen Raimo, Utriainen Pauliina, Laakso Markku, Jääskeläinen Jarmo

Abstract excerpt

Premature adrenarche (PA) has been associated with increased body mass index. Our aim was to determine whether the obesity-associated variant at fat mass and obesity gene (FTO) is more frequent in PA subjects. Furthermore, we hypothesized that altered Wnt signaling due to genetic variants at transcription factor 7-like 2 (TCF7L2) could play a role in the polygenic pathogenesis of PA. We genotyped polymorphisms at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19497595
DOI: 10.1016/j.metabol.2009.03.025

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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