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Article

Nutrient intake, weight, and Leu7Pro polymorphism in prepro-neuropeptide Y in children.

The Journal of clinical endocrinology and metabolism - 1 Nov 2006

Karvonen Matti K, Ruottinen Soile, Koulu Markku, Pesonen Ullamari, Niinikoski Harri, Rask-Nissilä Leena, Simell Olli, Rönnemaa Tapani

Abstract excerpt

CONTEXT: The important role of neuropeptide Y (NPY) in the regulation of food intake and energy balance has been firmly documented in rodents, but human data are sparse. The recently identified functional Leu7Pro polymorphism in the signal peptide region of the prepro-NPY is a useful tool for the investigation of the role of NPY in men. Pro7 substitution has been associated with the following: plasma NPY...

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Source

Identifiers

PMID: 16912140
DOI: 10.1210/jc.2005-2083

Genes

NPY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Nutrient intake, weight, and Leu7Pro polymorphism in prepro-neuropeptide Y in children.PMID 16912140Read ↗

Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene and changes in serum lipids during a family-based counselling intervention among school-aged children with a family history of CVD.Semantic proximity Read ↗

Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels.Semantic proximity Read ↗

Leucine 7 to Proline 7 Polymorphism in the Preproneuropeptide Y Is Associated with Birth Weight and Serum Triglyceride Concentration in Preschool-Aged ChildrenSemantic proximity Read ↗

Neuropeptide Y gene variants in obesity, dietary intake, blood pressure, lipid and glucose metabolism: A longitudinal birth cohort study.Semantic proximity Read ↗

The Leu7Pro polymorphism of preproNPY is associated with decreased insulin secretion, delayed ghrelin suppression, and increased cardiovascular responsiveness to norepinephrine during oral glucose tolerance test.Semantic proximity Read ↗

Leucine7 to proline7 polymorphism in the preproneuropeptide Y is associated with the progression of carotid atherosclerosis, blood pressure and serum lipids in Finnish menSemantic proximity Read ↗

Leu7Pro polymorphism of PreproNPY associated with an increased risk for type II diabetes in middle-aged subjects.Semantic proximity Read ↗

Polymorphisms in the NPY and AGRP genes and body fatness in Dutch adults.Semantic proximity Read ↗

The impact of the leucine 7 to proline 7 polymorphism of the neuropeptide Y gene on postprandial lipemia and on the response of serum total and lipoprotein lipids to a reduced fat diet.Semantic proximity Read ↗

Changes in diurnal sympathoadrenal balance and pituitary hormone secretion in subjects with Leu7Pro polymorphism in the prepro-neuropeptide Y.Semantic proximity Read ↗

NPY L7P polymorphism and metabolic diseasesSemantic proximity Read ↗

Neuropeptide Y polymorphism and alcohol consumption in middle-aged men.Semantic proximity Read ↗

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