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Article

LRP5 in premature adrenarche and in metabolic characteristics of prepubertal children.

Clinical endocrinology - 1 May 2009

Lappalainen Saila, Saarinen Anne, Utriainen Pauliina, Voutilainen Raimo, Jääskeläinen Jarmo, Mäkitie Outi

Abstract excerpt

OBJECTIVE: Premature adrenarche (PA) is associated with unfavourable metabolic characteristics. We hypothesized that genetic variation in low density lipoprotein (LDL) receptor-related protein 5 (LRP5), which is involved in Wnt signalling in the adrenal cortex and in cholesterol metabolism, plays a role in the pathogenesis of PA. DESIGN AND PATIENTS: We performed a cross-sectional association study in 73 Finnish...

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Source

Identifiers

PMID: 18721193
DOI: 10.1111/j.1365-2265.2008.03388.x

Genes

LRP5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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