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Article

The metabolic implications of aquaporin 7 (AQP7) promoter variants in lean children and children with obesity.

Hormones (Athens, Greece) - 1 Jun 2020

Oikonomou Eleni, Kostopoulou Eirini, Rojas-Gil Andrea Paola, Georgiou George, Spiliotis Bessie E

Abstract excerpt

PURPOSE: AQP7, a water/glycerol transporting protein, regulates adipocyte glycerol efflux and influences lipid and glucose homeostasis. Altered AQP7 expression in adults leads to impaired glycerol dynamics, adipocyte hypertrophy, and a predisposition to obesity and diabetes. AQP7 gene promoter variants lead to impaired AQP7-mediated adipocyte glycerol efflux and adipocyte hypertrophy. To assess its possible...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32146590
DOI: 10.1007/s42000-020-00184-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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