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Article

AKAP10 (I646V) functional polymorphism predicts heart rate and heart rate variability in apparently healthy, middle-aged European-Americans.

Psychophysiology - 1 May 2009

Neumann Serina A, Tingley Whittemore G, Conklin Bruce R, Shrader Catherine J, Peet Eloise, Muldoon Matthew F, Jennings J Richard, Ferrell Robert E, Manuck Stephen B

Abstract excerpt

Previous evidence suggests that the dual-specific A kinase-anchoring protein 2 functional polymorphism (AKAP10 (A/G) I646V) influences heart rate (HR) and heart rate variability (HRV) in mice and humans (N=122) with cardiovascular disease. Here, we asked whether this AKAP10 variant predicts HR and HRV in a large sample of healthy humans. Resting HR and short-term time and frequency domain measures of HRV (5 min...

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Share to A Kinase Anchor Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19496216
DOI: 10.1111/j.1469-8986.2009.00802.x
PMCID: PMC2890278

Genes

AKAP10

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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