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Article

Prolactin regulates ZNT2 expression through the JAK2/STAT5 signaling pathway in mammary cells

4 Jun 2009

Abstract excerpt

The zinc transporter ZnT2 (SLC30A2) plays an important role in zinc secretion into milk during lactation. The physiological process of mammary gland secretion is regulated through complex integration of multiple lactogenic hormones. Prolactin plays a primary role in this regulation through the activation of various signaling cascades including Jak2/STAT5, mitogen-activated protein kinase (MAPK), p38, and...

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PMID: 19494234
DOI: 10.1152/ajpcell.00589.2008

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