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Article

Mapping the zinc-transporting system in mammary cells: molecular analysis reveals a phenotype-dependent zinc-transporting network during lactation.

Journal of cellular physiology - 1 Apr 2012

Kelleher Shannon L, Velasquez Vanessa, Croxford Thomas P, McCormick Nicholas H, Lopez Veronica, MacDavid Joshua

Abstract excerpt

The mammary epithelial cell transitions from a non-secreting to a terminally differentiated, secreting cell during lactation. Zinc (Zn) is a key modulator of phenotypic transition as it regulates over 300 biological functions including transcription, translation, energy transformation, intracellular signaling, and apoptosis. In addition, Zn must be redirected from normal cellular functions into the secretory...

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Identifiers

PMID: 21702047
DOI: 10.1002/jcp.22900
PMCID: PMC3207005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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