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Article

Determinants of hepatitis C virus p7 ion channel function and drug sensitivity identified in vitro.

Journal of virology - 1 Aug 2009

StGelais Corine, Foster Toshana L, Verow Mark, Atkins Elizabeth, Fishwick Colin W G, Rowlands David, Harris Mark, Griffin Stephen

Abstract excerpt

Hepatitis C virus (HCV) chronically infects 170 million individuals, causing severe liver disease. Although antiviral chemotherapy exists, the current regimen is ineffective in 50% of cases due to high levels of innate virus resistance. New, virus-specific therapies are forthcoming although their development has been slow and they are few in number, driving the search for new drug targets. The HCV p7 protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19493992
DOI: 10.1128/JVI.00521-09
PMCID: PMC2715780

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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