Article
Fibrinogen gamma gene 3'-end polymorphisms and risk of venous thromboembolism in the African-American and Caucasian population.
Thrombosis and haemostasis - 1 Jun 2009
Uitte de Willige Shirley, Pyle Meridith E, Vos Hans L, de Visser Marieke C H, Lally Cathy, Dowling Nicole F, Hooper W Craig, Bertina Rogier M, Austin Harland
Abstract excerpt
Genetic determinants of venous thromboembolism (VTE) in the African-American population are poorly characterised. It was recently shown that fibrinogen gamma gene (FGG) polymorphisms 10034C>T and 9340T>C influence VTE risk in the Caucasian population. In the African-American population these polymorphisms are common, with allele frequencies above 25%. Here we evaluated whether these and other FGG 3'-end...
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