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Article

Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma' levels.

Blood - 15 Dec 2005

Uitte de Willige Shirley, de Visser Marieke C H, Houwing-Duistermaat Jeanine J, Rosendaal Frits R, Vos Hans L, Bertina Rogier M

Abstract excerpt

We investigated the association between haplotypes of fibrinogen alpha (FGA), beta (FGB), and gamma (FGG), total fibrinogen levels, fibrinogen gamma' (gammaA/gamma' plus gamma'/gamma') levels, and risk for deep venous thrombosis. In a population-based case-control study, the Leiden Thrombophilia Study, we typed 15 haplotype-tagging single nucleotide polymorphisms (htSNPs) in this gene cluster. None of these...

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Source

Identifiers

PMID: 16144795
DOI: 10.1182/blood-2005-05-2180

Genes

FGG
FGA
FGB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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