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Article

Genotypic influences on severity of exudative age-related macular degeneration.

Investigative ophthalmology & visual science - 1 May 2010

Leveziel Nicolas, Puche Nathalie, Richard Florence, Somner John E A, Zerbib Jennyfer, Bastuji-Garin Sylvie, Cohen Salomon Y, Korobelnik Jean-François, Sahel José, Soubrane Gisèle, Benlian Pascale, Souied Eric H

Abstract excerpt

PURPOSE: Major genetic risk factors have recently been identified for age-related macular degeneration (AMD), including the ARMS2/LOC387715 and CFH at-risk polymorphisms. The study was conducted to establish correlations between the AMD genotype and both the phenotype and severity of AMD. METHODS: In a prospective cohort of 1216 AMD patients, four genotypic homozygous groups were identified (n = 264): double...

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Source

Identifiers

PMID: 20042647
DOI: 10.1167/iovs.09-4423

Genes

ARMS2
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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