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Article

Haptoglobin genotype is a determinant of survival and cardiac remodeling after myocardial infarction in diabetic mice.

Cardiovascular diabetology - 2 Jun 2009

Asaf Roy, Blum Shany, Roguin Ariel, Kalet-Litman Shiri, Kheir Jad, Frisch Avi, Miller-Lotan Rachel, Levy Andrew P

Abstract excerpt

BACKGROUND: We have recently demonstrated in man that a functional allelic polymorphism in the Haptoglobin (Hp) gene plays a major role in determining survival and congestive heart failure after myocardial infarction (MI). We sought to recapitulate the effect of Hp type on outcomes and cardiac remodeling after MI in transgenic mice. METHODS: The Hp 2 allele exists only in man. Wild type C57Bl/6 mice carry the Hp...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19490627
DOI: 10.1186/1475-2840-8-29
PMCID: PMC2694779

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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