Article
Combined analysis of EGF+61G>A and TGFB1+869T>C functional polymorphisms in the time to androgen independence and prostate cancer susceptibility.
The pharmacogenomics journal - 1 Oct 2009
Teixeira A L, Ribeiro R, Morais A, Lobo F, Fraga A, Pina F, Calais-da-Silva F M, Calais-da-Silva F E, Medeiros R
Abstract excerpt
Proliferative mechanisms involving the epidermal growth factor (EGF) and transforming growth factor beta (TGF-beta(1)) ligands are potential alternative pathways for prostate cancer (PC) progression to androgen independence (AI). Thus, the combined effect of EGF and TGFB1 functional polymorphisms...
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