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Article

The TGF-β, PI3K/Akt and PTEN pathways: established and proposed biochemical integration in prostate cancer

23 Dec 2008

Abstract excerpt

A key to the development of improved pharmacological treatment strategies for cancer is an understanding of the integration of biochemical pathways involved in both tumorigenesis and cancer suppression. Furthermore, genetic markers that may predict the outcome of targeted pharmacological intervention in an individual are central to patient-focused treatment regimens rather than the traditional 'one size fits all'...

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Identifiers

PMID: 19099539
DOI: 10.1042/bj20081610

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