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Article

Signatures of positive selection in the cis-regulatory sequences of the human oxytocin receptor (OXTR) and arginine vasopressin receptor 1a (AVPR1A) genes.

BMC evolutionary biology - 13 May 2015

Schaschl Helmut, Huber Susanne, Schaefer Katrin, Windhager Sonja, Wallner Bernard, Fieder Martin

Abstract excerpt

BACKGROUND: The evolutionary highly conserved neurohypophyseal hormones oxytocin and arginine vasopressin play key roles in regulating social cognition and behaviours. The effects of these two peptides are meditated by their specific receptors, which are encoded by the oxytocin receptor (OXTR) and arginine vasopressin receptor 1a genes (AVPR1A), respectively. In several species, polymorphisms in these genes have...

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Identifiers

PMID: 25968600
DOI: 10.1186/s12862-015-0372-7
PMCID: PMC4429470

Genes

OXTR

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