Article
Non-A type nucleophosmin 1 gene mutation predicts poor clinical outcome in de novo adult acute myeloid leukemia: differential clinical importance of NPM1 mutation according to subtype.
International journal of hematology - 1 Jul 2009
Koh Youngil, Park Juwon, Bae Eun-Kyung, Ahn Kwang-Sung, Kim Inho, Bang Soo-Mee, Lee Jae-Hoon, Yoon Sung-Soo, Lee Dong Soon, Lee Young Yiul, Park Seonyang, Kim Byoung Kook
Abstract excerpt
Mutations of nucleophosmin gene (NPM1) are known to be related to good prognosis in AML patients lacking FLT3 internal tandem duplication (FLT3-ITD). Recently, NPM1 mutations other than type A were reported, but their clinical significance is not well known. Retrospective medical record review of...
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