Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cellular aging and senescence characteristics of human T-lymphocytes.

Biogerontology - 1 Apr 2012

Onyema Oscar Okwudiri, Njemini Rose, Bautmans Ivan, Renmans Wim, De Waele Marc, Mets Tony

Abstract excerpt

CD28-, CD57+ and KLRG1+ are cell surface markers that have been used to describe senescent T-lymphocytes in humans. However, the relationship among these phenotypes during aging, and their relationship with the concept of in vitro cellular aging have not been well established. Using five-colour flow cytometry, we analyzed peripheral blood T-lymphocytes for their expression of CD28, CD57 and KLRG1 in 11 young (Y)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD28 Antigens
Share to CD57 Antigens
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Cyclin-Dependent Kinase Inhibitor p21

Share to Lectins, C-Type

Share to Receptors, Immunologic

Share to T-Lymphocyte Subsets

Source

Identifiers

PMID: 22102004
DOI: 10.1007/s10522-011-9366-z

Genes

KLRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cellular aging and senescence characteristics of human T-lymphocytes.PMID 22102004Read ↗

Aging-associated subpopulations of human CD8+ T-lymphocytes identified by their CD28 and CD57 phenotypes.Semantic proximity Read ↗

Markers of immunosenescence in CMV seropositive healthy elderly adultsSemantic proximity Read ↗

Are immunosenescent T cells really senescent?Semantic proximity Read ↗

Immunosenescence Study of T Cells: A Systematic Review.Semantic proximity Read ↗

Markers of T Cell Senescence in HumansSemantic proximity Read ↗

γ/δ T cell subsets in human aging using the classical α/β T cell modelSemantic proximity Read ↗

Senescent phenotypes and telomere lengths of peripheral blood T-cells mobilized by acute exercise in humans.Semantic proximity Read ↗

CD8+ CD28− and CD8+ CD57+ T cells and their role in health and diseaseSemantic proximity Read ↗

Senescence‐associated β‐galactosidase reveals the abundance of senescent CD8+ T cells in aging humansSemantic proximity Read ↗

Impact of age, sex and CMV-infection on peripheral T cell phenotypes: results from the Berlin BASE-II Study.Semantic proximity Read ↗

KLRG1--more than a marker for T cell senescence.Semantic proximity Read ↗

Immunosenescence markers in T- and NK-cells according to the CD4/CD8 ratio in successfully treated people living with HIVSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.