Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP19 haplotypes increase risk for Alzheimer’s disease

1 Aug 2006

Abstract excerpt

Cytochrome P450 aromatase, an enzyme that catalyses the conversion of androgens to oestrogen, is expressed at high levels in the gonads and in the brain. Aromatase activity is increased in the nucleus basalis of Meynert during aging and in Alzheimer's disease (AD), making the gene (CYP19), at 15q21.1, a potential candidate risk factor. We examined 18 single nucleotide polymorphisms spanning the 5'-untranslated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estrogen and related hormone effects
Share to Hormonal Regulation and Hypertension
Share to Menopause: Health Impacts and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16882736
DOI: 10.1136/jmg.2005.039461

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP19 haplotypes increase risk for Alzheimer’s diseasePMID 16882736Read ↗

Polymorphisms in the CYP19 gene confer increased risk for Alzheimer disease.Semantic proximity Read ↗

Genetic variation of CYP19 (aromatase) gene influences age at onset of Alzheimer's disease in women.Semantic proximity Read ↗

The CYP19A1 rs3751592 variant confers susceptibility to Alzheimer disease in the Chinese Han population.Semantic proximity Read ↗

Interaction between CYP19 aromatase and butyrylcholinesterase genes increases Alzheimer's disease risk.Semantic proximity Read ↗

Aromatase enzyme and Alzheimer's disease.Semantic proximity Read ↗

Haplotype analyses of CYP19A1 gene variants and breast cancer risk: results from the Shanghai Breast Cancer Study.Semantic proximity Read ↗

Aromatase variants modify risk for Alzheimer's disease in a multiethnic female cohort.Semantic proximity Read ↗

<i>CYP19</i> (aromatase) haplotypes and endometrial cancer riskSemantic proximity Read ↗

Identification of CYP19A1 single-nucleotide polymorphisms and their haplotype distributions in a Korean population.Semantic proximity Read ↗

Variants in CYP17 and CYP19 cytochrome P450 genes are associated with onset of Alzheimer's disease in women with down syndrome.Semantic proximity Read ↗

Association of the aromatase gene with Alzheimer's disease in women.Semantic proximity Read ↗

A comprehensive examination of CYP19 variation and risk of breast cancer using two haplotype-tagging approaches.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.