Article
Therapeutic effect of {beta}-adrenoceptor blockers using a mouse model of dilated cardiomyopathy with a troponin mutation.
Cardiovascular research - 1 Oct 2009
Zhan Dong-Yun, Morimoto Sachio, Du Cheng-Kun, Wang Yuan-Yuan, Lu Qun-Wei, Tanaka Atsushi, Ide Tomomi, Miwa Yoshikazu, Takahashi-Yanaga Fumi, Sasaguri Toshiyuki
Abstract excerpt
AIMS: Extensive clinical studies have demonstrated that beta-adrenoceptor blocking agents (beta-blockers) are beneficial in the treatment of chronic heart failure, which is due to various aetiologies, including idiopathic dilated cardiomyopathy (DCM) and ischaemic heart disease. However, little is known about the therapeutic efficacy of beta-blockers in the treatment of the inherited form of DCM, of which...
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