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Article

Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy.

PloS one - 1 Jan 2012

Suzuki Takeshi, Shioya Takao, Murayama Takashi, Sugihara Masami, Odagiri Fuminori, Nakazato Yuji, Nishizawa Hiroto, Chugun Akihito, Sakurai Takashi, Daida Hiroyuki, Morimoto Sachio, Kurebayashi Nagomi

Abstract excerpt

BACKGROUND: Patients with inherited dilated cardiomyopathy (DCM) frequently die with severe heart failure (HF) or die suddenly with arrhythmias, although these symptoms are not always observed at birth. It remains unclear how and when HF and arrhythmogenic changes develop in these DCM mutation ca...

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Share to Arrhythmias, Cardiac
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22514734
DOI: 10.1371/journal.pone.0035353
PMCID: PMC3325934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22514734-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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