Article
Computational investigation of epithelial cell dynamic phenotype in vitro.
Theoretical biology & medical modelling - 28 May 2009
Kim Sean H J, Park Sunwoo, Mostov Keith, Debnath Jayanta, Hunt C Anthony
Abstract excerpt
BACKGROUND: When grown in three-dimensional (3D) cultures, epithelial cells typically form cystic organoids that recapitulate cardinal features of in vivo epithelial structures. Characterizing essential cell actions and their roles, which constitute the system's dynamic phenotype, is critical to gaining deeper insight into the cystogenesis phenomena. METHODS: Starting with an earlier in silico epithelial analogue...
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