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Methylation profile of circulating plasma DNA in patients with pancreatic cancer

8 Dec 2008

Abstract excerpt

BACKGROUND AND OBJECTIVES: Detection of pancreatic cancer by blood-based test may improve outcomes. We sought to establish the feasibility of a blood-based detection of pancreatic cancer through multiplexed array-mediated analysis of DNA methylation. METHODS: Methylation was assessed in each plasma sample using a panel of 56 frequently methylated genes. Methylation profiles in patients with ductal cell...

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PMID: 19065635
DOI: 10.1002/jso.21208

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