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Assessment of gene promoter hypermethylation for detection of cervical neoplasia

30 May 2006

Abstract excerpt

Current cervical cancer screening is based on morphological assessment of Pap smears and associated with significant false negative and false positive results. Previously, we have shown that detection of hypermethylated genes in cervical scrapings using quantitative methylation-specific PCR (QMSP) is a promising tool for identification of squamous cell cervical cancer. Aim of the present pilot-study was to...

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PMID: 16736496
DOI: 10.1002/ijc.22060

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