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Acute promyelocytic leukemia: from highly fatal to highly curable

25 Feb 2008

Abstract excerpt

Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia. Morphologically, it is identified as the M3 subtype of acute myeloid leukemia by the French-American-British classification and cytogenetically is characterized by a balanced reciprocal translocation between chromosomes 15 and 17, which results in the fusion between promyelocytic leukemia (PML) gene and retinoic acid receptor...

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PMID: 18299451
DOI: 10.1182/blood-2007-07-102798

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