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β3‐Tubulin is induced by estradiol in human breast carcinoma cells through an estrogen‐receptor dependent pathway

22 May 2009

Abstract excerpt

Microtubules are involved in a variety of essential cell functions. Their role during mitosis has made them a target for anti-cancer drugs. However development of resistance has limited their use. It has been established that enhanced beta3-tubulin expression is correlated with reduced response to antimicrotubule agent-based chemotherapy or worse outcome in a variety of tumor settings. However little is known...

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PMID: 19466750
DOI: 10.1002/cm.20377

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