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Article

Taxol Resistance Among the Different Histological Subtypes of Ovarian Cancer May Be Associated With the Expression of Class III β-Tubulin

1 Feb 2008

Abstract excerpt

The prognostic significance of histology has been well established in epithelial ovarian cancer (EOC). Clear cell and mucinous histologies are especially generally accepted to result in an adverse outcome because of their poor chemotherapy response. Previous reports suggested that class III beta-tubulin induced taxol resistance in association with a reduced effect on microtubule dynamic instability. Thus, this...

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Share to 14-3-3 protein interactions
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PMID: 18317222
DOI: 10.1097/pgp.0b013e318156c838

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