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Host sensing and signal transduction during Toxoplasma stage conversion

29 Oct 2020

Abstract excerpt

The intracellular parasite Toxoplasma gondii infects nucleated cells in virtually all warm-blooded vertebrates, including one-third of the human population. While immunocompetent hosts do not typically show symptoms of acute infection, parasites are retained in latent tissue cysts that can be reactivated upon immune suppression, potentially damaging key organ systems. Toxoplasma has a multistage life cycle that...

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PMID: 33118234
DOI: 10.1111/mmi.14634

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